How does azelaic acid work on acne-prone skin?

Azelaic acid helps balance acne-prone skin through several mechanisms relevant to formulators. It has antibacterial activity that targets specific opportunistic organisms such as Cutibacterium acnes (formerly Propionibacterium acnes) and Staphylococcus epidermidis, it is comedolytic, and it supports sebum regulation. Its activity is limited to opportunistic organisms and does not disturb the commensal skin flora.